Taylor started taking Palladia chemo pills 4 weeks ago.
100 mg, Monday, Wednesday, and Friday.
He has shown no side effects, and his blood test last week showed all within normal greyhound ranges.
A couple of days ago, I noticed some pigmentation change on his nose:
I sent the following email to his oncologist last evening, followed by the doctor's response:
Starting a day or two ago, I noticed the pigmentation on Taylor's nose seems to have changed.
It seems a little more brown or reddish brown.
Not black.
It's not scaly and it isn't bothering him.
His appetite and activity level are fine.
Actually, the past few days he's been VERY active, wanting to get out for rides and walks as often as he can talk me into it.
Naturally, it's boiling hot out.
Any idea what might be going on?
Related to his condition?
Related to his chemo?
His reply:
Hi,
I believe this is most likely related to starting Palladia. A skin pigment change is reported in some dogs in the original studies. I have seen this quite a few times, sometimes quite profoundly. As long as it is not scaly or cracking, and of course not bothering him, then it should be fine. It may continue to change and you may notice a change in his hair color as well. No one really knows why this happens with Palladia, but it seems to be purely cosmetic. I am glad that he is feeling so well! Thank you Evan Sones, DVM, MS DACVIM (Oncology) Animal Cancer Care Clinic 954-527-3111 www.animalcancercareclinic.com