Desi went through this a couple of years ago.....exactly as you are describing....lesions around nails, but nails
intact, not loose.
After going through much of the same testing, we decided to try Atopica (cyclosporine). He was on 100 mg twice a day
and lesions were much better in just a couple of weeks. After a month or so, down to 100 mg once a day for a few
months, then 3 times a week for quite a while. All this time, toes were fine, but I was afraid to stop the cyclosporin
completely in case the lesions returned. After about a year, we were down to once weekly.....then I started to forget
and it was once every couple of weeks, and then I'd forget again.... So, I finally just stopped. That's been 2
years ago, and lesions have never returned.
In Desi's case, the Cyclosporine did not have the side effects of excessive drinking/urinations, but he did have
yucky soft poo. Soft to the point that I carried a paper plate to catch it...it was impossible to clean up out of the
grass. That lasted through the twice a days and some into the once a day, but eventually, all was well.