Mo,
I went through chemo with Rascal for Lymphoma. It has been several years ago now so I don't remember the drug names anymore. His treatments were fairly short...inserted an IV into his leg and put the drugs in. He was also on oral meds in the initial treatment. He would be extra tired the next day but always rebounded pretty quickly. My vet recommended pred which had the great side effect of getting them to eat. We didn't do that due to Rascal having no bowel or bladder control but he ate fairly well through it. I never had to leave him for treatment and I believe we went once a week for 6 weeks.
I have some Fresh Factors if you would like to try them I would be happy to send you a bottle to see if it helps.