Denamarin needs to be in the intestine to provide the most good, hence the fast. Disco's ER Vet was adamant about the 2 hour rule. We are allowed to give the tab with a pill pocket.
For Disco, I simply set my alarm at the appointed time, gave him the Denamarin and went back to bed. Although, I work nights and we just don't feed him or give any treats after 3 a.m.. But we went though over two months of a plethora of daily meds. at timed intervals, resulting in many alarms and lack of sleep.
I am not trying to argue with tbhounds. I am simply parroting the information our ER Vet gave us.