iluvgreys Posted August 27, 2008 Share Posted August 27, 2008 (edited) See INFO HERE for description of study and link for directions on how to submit a blood sample. Blood samples from pure breeds of any of these groups are needed: Rottweilers, Greyhounds, Mastiffs, Leonbergers, Golden Retrievers, Irish Wolfhounds, Great Pyrenees, Great Danes, Borzoi and Scottish Deerhounds There's a link for those in Europe, too. Since the above link is not working reliably, here's the info it contains: http://www.broad.mit.edu/mammals/dog/donate.html# How can your dog help? This important research cannot proceed without the dog community's participation. We need DNA samples from purebred dogs suffering from the diseases we are studying (described below), as well as from older, healthy dogs from the breeds we are studying. Osteosarcoma (Bone cancer) Breeds needed for our study: Rottweilers, Greyhounds, Mastiffs, Leonbergers, Golden Retrievers, Irish Wolfhounds, Great Pyrenees, Great Danes, Borzoi and Scottish Deerhounds Main collaborators: Kenine Comstock (The University of Michigan), Jaime Modiano (University of Minnesota), Cheryl London (Ohio State University), Elizabeth McNeil (Michigan State University), Matthew Breen (North Carolina State University) Funding: AKC/CHF If you have questions, please contact us: E-mail: dog-info@broad.mit.edu Please use links as titled below for more information. Sending DNA samples Information for veterinarians Dr. Couto -“We are working with Dr. Comstock in Michigan looking at genetics of bone tumors.†2007/2008 Orthopedic Foundation for Animals Research Funding Morris Animal Foundation Grant # MAF-D06CA-066 Research Institution: The Broad Institute Title: Mapping Genes Associated With Canine Mast Cell Tumors Researchers: Dr. Kerstin Lindblad-Toh Abstract: Mast cell tumors (MCT) are the most common skin tumors in dogs. Survival rates are dependent upon the tumor grade. While dogs with grade 1 tumors often experience long-term survival, those with grade 3 tumors usual die within six months. This cancer has a particularly high occurrence in certain breeds, which suggests a significant genetic component. This study will use a new approach to identify genes that contribute to an increased risk of developing mast cell cancer in golden retrievers and related breeds. Identifying these genes will help scientists rapidly develop genetic tests that would indicated a predisposition to this cancer and would help develop therapeutic strategies based on tumor grade. AKC Canine Health Foundation Grant # 778 Research Institution: Colorado State University Title: Role of Regulatory T Cells in Dogs with Osteosarcoma Researchers: Dr. Steve Dow View Abstract: www.akcchf.org/research/grants/search/index.cfm?search=number&display=results&number=778 Data Sheet: Mast Cell Tumors or Osteosarcoma Research Organization: Broad Institute Contact Person: Not applicable Contact Phone: Not applicable Email Address: info@broad.mit.edu Project Web Site: http://www.broad.mit.edu/mammals/dog/ About This Disease Mast cell tumors (MCT) are cancerous proliferations of mast cells. Although they can and will spread throughout the body, the danger from mast cell tumors arises from the secondary damage caused by the release of chemicals that they produce. These chemicals can cause systemic problems that include gastric ulcers, internal bleeding, and a range of allergic manifestations. Clearly, mast cell tumors affect both lifespan and quality of life. Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the metaphyseal region of tubular long bones. It is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone. About This Research Project This study attempts to map risk factors for mast cell tumors or osteosarcoma respectively. What is Needed? (if you participate) If you suspect that your dog has a mast cell tumor or osteosarcoma, please contact the Broad Institute at the email address above and ask how to proceed to submit a blood sample to participate. Europe http://www.pet-screen.com/web/PETSCR/index...=3&dir=5222 Edited August 27, 2008 by iluvgreys Quote Jeanne with Remington & Scooter the cat....and Beloved Bridge Angels Sandee, Shari, Wells, Derby, Phoenix, Jerry Lee and Finnian.....If tears could build a stairway, and memories a lane, I'd walk right up to heavenand bring you home again. Link to comment Share on other sites More sharing options...
CaliforniaGreys Posted August 27, 2008 Share Posted August 27, 2008 The link wouldn't come up for me Quote Missing my little Misty who took a huge piece of my heart with her on 5/2/09, and Ekko, on 6/28/12 For the sick, the lost, and the homeless Link to comment Share on other sites More sharing options...
5blackgreys Posted August 27, 2008 Share Posted August 27, 2008 I couldn't get the link to work either. Quote , Phoenix, Okie, Casey, and Ellie the Galga; with Aggie, Alexa, Bear,Cody, Gianni V., Missy B, Babette, Bernice, and BooBoo at the Bridge Link to comment Share on other sites More sharing options...
dmdsmoxie Posted August 27, 2008 Share Posted August 27, 2008 I clicked on the link earlier today and it worked, now it doesn't. It might be the site and not the link. Dick Quote Link to comment Share on other sites More sharing options...
Guest nerak254 Posted August 27, 2008 Share Posted August 27, 2008 I couldn't get it to work either Quote Link to comment Share on other sites More sharing options...
ahicks51 Posted August 27, 2008 Share Posted August 27, 2008 Based on a Google search for the breeds listed, the study seems to come from here: http://www.broad.mit.edu/mammals/dog/donate.html Sample submission instructions should be in there somewhere. They're also looking for other breeds as concerned with other types of cancer. Quote Coco (Maze Cocodrillo) Minerva (Kid's Snipper) Link to comment Share on other sites More sharing options...
Bevd Posted August 27, 2008 Share Posted August 27, 2008 The link under the red line of text is working but the top one is not. The bottom link for europe works for me too. We sent a sample of Darcys blood to the place in the bottom link Quote Deerhounds Darcy, Duffy, Grace & Wellington, Mutts Sprout & Buddy, Lurchers Ned & Jake plus Ella the Westie + cats. Remembering Del, Jessie, Maddison, Flo, Sally, Stanley, Wallace, Radar, Mokka, Oki cat, Tetley, Poppy & Striker. Please visit our web store at http://www.dogsndubs.com for our own range of Greyhound related clothing for humans! Link to comment Share on other sites More sharing options...
Guest greytexplorer Posted August 27, 2008 Share Posted August 27, 2008 What is the cost involved? We also have a purebred chihuahua. Would "they" be interested in a blood sample from him as well? Quote Link to comment Share on other sites More sharing options...
iluvgreys Posted August 27, 2008 Author Share Posted August 27, 2008 (edited) What is the cost involved? We also have a purebred chihuahua. Would "they" be interested in a blood sample from him as well? In this link, http://www.broad.mit.edu/mammals/dog/donate.html click on the instructions for the vet (maybe even print them out for your vet) and ask your vet how much they would charge you for the blood draw and mailing. Right now they're studying large breeds only, so it seems. I plan to have some of Finnian's blood sent, the next time he's due for a vet visit. I requested clarification from the study as to the age of "healthy dogs" that they're needing samples from. This was her reply. "Hi Jeanne, For the older healthy dogs we usually try to collect samples from dogs that are 5 and older, any dog that is affected with cancer/disease at any age we would also greatly appreciate. Thank you so much for your help we are always looking for more samples! If you or anyone else has any adddtional questions please feel free to contact me at any time my email address is perloski@broad.mit.edu or 617-324-5025. Thank you again! Michele Perloski" Then I requested more clarification as to the breeds of dogs they're needing and types of cancers/diseases. Here's her response. Hi Jeanne, Any pure breed dog that is affected we are collecting, the list of samples are dogs that we need currently. However, we like to add additional breeds to our studies but we do not have enough samples to add the to the studies So the more the better For your question on other types of cancers, we are working on other cancers such as lymphoma, hemangiosarcoma and autoimmune diseases (example- epilepsy). So any pure breed dog that is affected with any type of cancer/disease would be a great help! The reason we ask for pure breed dogs is when we do our studies we look at their pedigrees to see if any of the dogs have any relationship to each other. Thank you so much for getting the word out there, we greatly appreciate any samples that we can get! Thanks! Michele If there's any more questions about this study, just give Michele a call at 617-324-5025 or send her an email at perloski@broad.mit.edu Edited August 27, 2008 by iluvgreys Quote Jeanne with Remington & Scooter the cat....and Beloved Bridge Angels Sandee, Shari, Wells, Derby, Phoenix, Jerry Lee and Finnian.....If tears could build a stairway, and memories a lane, I'd walk right up to heavenand bring you home again. Link to comment Share on other sites More sharing options...
CaliforniaGreys Posted August 27, 2008 Share Posted August 27, 2008 Thanks for posting this. Misty is due for blood work again, and I can also bring Wayne in as well. Quote Missing my little Misty who took a huge piece of my heart with her on 5/2/09, and Ekko, on 6/28/12 For the sick, the lost, and the homeless Link to comment Share on other sites More sharing options...
iluvgreys Posted August 27, 2008 Author Share Posted August 27, 2008 We also have a purebred chihuahua. Would "they" be interested in a blood sample from him as well? Please see add'l info I posted in #9. Apparently they would like blood from other healthy breeds besides the big dogs. Quote Jeanne with Remington & Scooter the cat....and Beloved Bridge Angels Sandee, Shari, Wells, Derby, Phoenix, Jerry Lee and Finnian.....If tears could build a stairway, and memories a lane, I'd walk right up to heavenand bring you home again. Link to comment Share on other sites More sharing options...
Guest greytexplorer Posted August 27, 2008 Share Posted August 27, 2008 awww cr@p can't send them DickCheney's blood sample, cuz I don't have an AKC number for him well, maybe they don't want his blood sample anyway, since he is on heart medications Quote Link to comment Share on other sites More sharing options...
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