iluvgreys Posted August 27, 2008 Share Posted August 27, 2008 (edited) See INFO HERE for description of study and link for directions on how to submit a blood sample. Blood samples from pure breeds of any of these groups are needed: Rottweilers, Greyhounds, Mastiffs, Leonbergers, Golden Retrievers, Irish Wolfhounds, Great Pyrenees, Great Danes, Borzoi and Scottish Deerhounds There's a link for those in Europe, too. Since the above link is not working reliably, here's the info it contains: http://www.broad.mit.edu/mammals/dog/donate.html# How can your dog help? This important research cannot proceed without the dog community's participation. We need DNA samples from purebred dogs suffering from the diseases we are studying (described below), as well as from older, healthy dogs from the breeds we are studying. Osteosarcoma (Bone cancer) Breeds needed for our study: Rottweilers, Greyhounds, Mastiffs, Leonbergers, Golden Retrievers, Irish Wolfhounds, Great Pyrenees, Great Danes, Borzoi and Scottish Deerhounds Main collaborators: Kenine Comstock (The University of Michigan), Jaime Modiano (University of Minnesota), Cheryl London (Ohio State University), Elizabeth McNeil (Michigan State University), Matthew Breen (North Carolina State University) Funding: AKC/CHF If you have questions, please contact us: E-mail: email@example.com Please use links as titled below for more information. Sending DNA samples Information for veterinarians Dr. Couto -â€œWe are working with Dr. Comstock in Michigan looking at genetics of bone tumors.â€ 2007/2008 Orthopedic Foundation for Animals Research Funding Morris Animal Foundation Grant # MAF-D06CA-066 Research Institution: The Broad Institute Title: Mapping Genes Associated With Canine Mast Cell Tumors Researchers: Dr. Kerstin Lindblad-Toh Abstract: Mast cell tumors (MCT) are the most common skin tumors in dogs. Survival rates are dependent upon the tumor grade. While dogs with grade 1 tumors often experience long-term survival, those with grade 3 tumors usual die within six months. This cancer has a particularly high occurrence in certain breeds, which suggests a significant genetic component. This study will use a new approach to identify genes that contribute to an increased risk of developing mast cell cancer in golden retrievers and related breeds. Identifying these genes will help scientists rapidly develop genetic tests that would indicated a predisposition to this cancer and would help develop therapeutic strategies based on tumor grade. AKC Canine Health Foundation Grant # 778 Research Institution: Colorado State University Title: Role of Regulatory T Cells in Dogs with Osteosarcoma Researchers: Dr. Steve Dow View Abstract: www.akcchf.org/research/grants/search/index.cfm?search=number&display=results&number=778 Data Sheet: Mast Cell Tumors or Osteosarcoma Research Organization: Broad Institute Contact Person: Not applicable Contact Phone: Not applicable Email Address: firstname.lastname@example.org Project Web Site: http://www.broad.mit.edu/mammals/dog/ About This Disease Mast cell tumors (MCT) are cancerous proliferations of mast cells. Although they can and will spread throughout the body, the danger from mast cell tumors arises from the secondary damage caused by the release of chemicals that they produce. These chemicals can cause systemic problems that include gastric ulcers, internal bleeding, and a range of allergic manifestations. Clearly, mast cell tumors affect both lifespan and quality of life. Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the metaphyseal region of tubular long bones. It is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone. About This Research Project This study attempts to map risk factors for mast cell tumors or osteosarcoma respectively. What is Needed? (if you participate) If you suspect that your dog has a mast cell tumor or osteosarcoma, please contact the Broad Institute at the email address above and ask how to proceed to submit a blood sample to participate. Europe http://www.pet-screen.com/web/PETSCR/index...=3&dir=5222 Edited August 27, 2008 by iluvgreys Quote Jeanne with Remington & Scooter the cat....and Beloved Bridge Angels Sandee, Shari, Wells, Derby, Phoenix, Jerry Lee and Finnian.....If tears could build a stairway, and memories a lane, I'd walk right up to heavenand bring you home again. Link to comment Share on other sites More sharing options...
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