I've been especially missing my boy, Keno, recently. He left us in January and the impact of his loss still comes in waves. Anyway, he had LP (laryngeal paralysis), LS (lumbosacral stenosis), and other neurological symptoms that appeared to be autoimmune in origin. Being an avid internet researcher, I compiled lots of info on his variety of symptoms and passed these along to my vet as we tried to piece together what was going on with him in the beginning. I came across this folder in my favorites today and I thought posting this might help someone who's struggling with their dog's health issues.
It's not always the case, but indicated in some of these problems (and in some dogs) is hypothyroidism. Because Keno didn't seem to exhibit any of the "classic symptoms" of hypothyroidism, my vet didn't think adding a complete thyroid panel to our long list of tests was necessary, but did it at my request and sent it to Michigan. He was very surprised when Keno's lab results showed he was extremely hypothyroid (very low thyroid function even for a greyhound). And all without many of the classic symptoms -- hair loss, weigh gain, cold intolerance, etc. We started him on medication right away, but sadly, I had to help him to the bridge only a fews weeks later.
Even if your hound isn't showing the classic low thyroid symptoms, hypothyroidism or autoimmune thyroid disease could be contributing to his/her neurological and/or autoimmunity problems. Not all vets agree that there is a relationship, but many do. Dr. Jean Dodds is one of them. She believes animals with autoimmune thyroid disease have generalized metabolic imbalance and often have associated immunological/neurological dysfunction.
I'm not sure it would have made a difference for my beloved Keno, but I will always wonder if I had insisted on a thyroid panel earlier (and his thyroid function was corrected) would he have gone into such rapid decline with multiple neurological (polyneuropathy) and autoimmune problems.
Just something to think about, research, talk to your vet about if your dog is having some of these problems.