From OSU website:
Pain control is essential in dogs where surgery is not an option; we have used either NSAIDs (carprofen, deracoxib, meloxicam) at recommended doses, or bisphosphonates such as alendronate (Fosamax®), at a dose of 10 mg/dog once a day or pamidronate (Aredia®), at a dose of 1 mg/kg, IV as a 30-minute CRI, every 3 to 6 weeks. Drugs such as tramadol (Ultram) at dosages of 1-2 mg/kg, PO, q8-12h may also be beneficial.