4My2Greys
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Posts posted by 4My2Greys
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Please check out the thread Effects of Manuka honey for IBD and consider using it before you use the Imuran.
ETA: Especially if the mucousy poop is a result of the inflammation. The study showed that Manuka honey significantly reduced colonic inflammation.
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I’m not sure how it could be applied to dogs , but here is another upcoming study which will be interesting to see the results of:
A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer
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So, 'just had a flare of the gurglies Sunday (actually Sweetpea did
).As usual, the first clue she gives that the gurglies are imminent is turning up her nose at breakfast.
Since breakfast was a little later than normal, I could also hear gurgle-murmurs tuning up in her tummy.
'Gave her a tsp of Manuka, went on with the rest of our day. (The gurgles stopped in about 20 minutes.)
At approximately midway between breakfast and dinner I gave her another tsp of honey.
At dinner time (6pm) gave her a tsp of honey, then she marched into her closet and ate her meal.
For comparison, before when the gurglies came, it would be at least two days of pepcid (and no eating)
and we'd have to wait until she passed a greasy noxious poop before she'd get her appetite back and
start eating again.
Since we started Manuka, we resolve the gurgles in less than one day, and it never travels to her lower GI; her
poops stay the same.
Purely anecdotal, I know, but it might work just as well in some other hound, and it sure does wonders for my peace of mind.
I mean, Sweetpea isn't carrying around any extra weight, so 2 to 3 days of not eating was pretty stressful for me!
Toodles,
Buzzy
Buzzy I'm so glad that this is working so well for Sweetpea. Nadir does the same thing with turning his nose away from his food that I know trouble is brewing. As soon as he does this I give him the Manuka honey. He also like Sweetpea doesn't carry extra weight and I was having the hardest time keeping weight on him because of his digestive system troubles.
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Here is my understanding of the rating systems. If it has the UMF or MGO seal, it is guaranteed to have the active properties to the number rating on the jar. If it doesn't have the UMF or MGO rating, it is said not to be guranteed to be as active as the jar may indicate. (I think there have been some scammers selling this stuff, which is why they came up with the rating systems.) Anything UMF rated will be much more expensive than anything labeled active. HOWEVER, I use a hi-actve 16+ from Whole Foods and it works great. My personal opinion is, if you get it from a reputable source, it will be the real deal. I would buy UMF rated if it was available, but I have't seen it in any stores close by. There is lots of info about the 2 rating systems on the web also.
I agree with you on getting it from a reputable source. I've had success with both the Hi-Active 15+ and 16+ jars I have bought and they do not have a UMF or MGO rating. I did find this article though that says that the MGO rating is the preferred rating scale.
http://www.nbr.co.nz/article/study-adds-further-fuel-manuka-honey-testing-debate-103046
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I don't go in for a lot of what is often called "alternative medicine," and I wasn't totally bowled over by the rat study .... but this seems to me at the very least, "can't hurt, might help." If I had a dog with serious digestive issues, I'd likely be trying it.
I'm glad to see that you of all people would consider trying it. I think the study says a heck of a lot for Manuka honey especially when you take the other study on safety of Manuka honey into consideration. According to the rat study there was significant protection with Manuka honey. All treated groups showed reduced colonic inflammation, however compare the safety of Manuka honey to the following possible side effects of Sulfasalazine, which is often prescribed, that was also part of this study.
The most common adverse reactions associated with Sulfasalazine are anorexia, headache, nausea, vomiting, gastric distress, and apparently reversible oligospermia. These occur in about one-third of the patients. Less frequent adverse reactions are skin rash, pruritus, urticaria, fever, Heinz body anemia, hemolytic anemia, and cyanosis, which may occur at a frequency of one in every thirty patients or less. Experience suggests that with a daily dosage of 4 g or more, or total serum sulfapyridine levels above 50 mcg/mL, the incidence of adverse reactions tends to increase. Although the listing which follows includes a few adverse reactions which have not been reported with this specific drug, the pharmacological similarities among the sulfonamides require that each of these reactions be considered when Sulfasalazine tablets are administered. Less common or rare adverse reactions include:
Blood dyscrasias: aplastic anemia, agranulocytosis, leukopenia, megaloblastic (macrocytic) anemia, purpura, thrombocytopenia, hypoprothrombinemia, methemoglobinemia, congenital neutropenia, and myelodysplastic syndrome.
Hypersensitivity reactions: erythema multiforme (Stevens-Johnson syndrome), exfoliative dermatitis, epidermal necrolysis (Lyell's syndrome) with corneal damage, drug rash with eosinophilia and systemic symptoms (DRESS), anaphylaxis, serum sickness syndrome, interstital lung disease, pneumonitis with or without eosinophilia, vasculitis, fibrosing alveolitis, pleuritis, pericarditis with or without tamponade, allergic myocarditis, polyarteritis nodosa, lupus erythematosus-like syndrome, hepatitis and hepatic necrosis with or without immune complexes, fulminant hepatitis, sometimes leading to liver transplantation, parapsoriasis varioliformis acuta (Mucha-Haberman syndrome), rhabdomyolysis, photosensitization, arthralgia, periorbital edema, conjunctival and scleral injection, and alopecia.
Gastrointestinal reactions: hepatitis, hepatic failure, pancreatitis, bloody diarrhea, impaired folic acid absorption, impaired digoxin absorption, stomatitis, diarrhea, abdominal pains, and neutropenic enterocolitis.
Central nervous system reactions: transverse myelitis, convulsions, meningitis, transient lesions of the posterior spinal column, cauda equina syndrome, Guillian-Barre syndrome, peripheral neuropathy, mental depression, vertigo, hearing loss, insomnia, ataxia, hallucinations, tinnitus, and drowsiness.
Renal reactions: toxic nephrosis with oliguria and anuria, nephritis, nephrotic syndrome, urinary tract infections, hematuria, crystalluria, proteinuria, and hemolytic-uremic syndrome.
Other reactions: urine discoloration and skin discoloration.
The sulfonamides bear certain chemical similarities to some goitrogens, diuretics (acetazolamide and the thiazides), and oral hypoglycemic agents. Goiter production, diuresis and hypoglycemia have occurred rarely in patients receiving sulfonamides. Cross-sensitivity may exist with these agents. Rats appear to be especially susceptible to the goitrogenic effects of sulfonamides and long-term administration has produced thyroid malignancies in this species.
Postmarketing Reports
The following events have been identified during post-approval use of products which contain (or are metabolized to) mesalamine in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. These events have been chosen for inclusion due to a combination of seriousness, frequency of reporting, or potential causal connection to mesalamine:
Gastrointestinal: Reports of hepatotoxicity, including elevated liver function tests (SGOT/AST, SGPT/ALT, GGT, LDH, alkaline phosphatase, bilirubin),jaundice,cholestatic jaundice,cirrhosis,and possible hepatocellular damage including liver necrosis and liver failure. Some of these cases were fatal. One case of Kawasaki-like syndrome, which included hepatic function changes, was also reported.
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20011, and check the box up top for endocrinologist's interpretation. Best luck!
THANK YOU!
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My friend who I started the other thread about is going to have a full thyroid panel done by MSU. Which code is the one that she needs to use? Is it 20011 or 20013
http://www.animalhea...DM.FORM.007.pdf
Thanks in advance for your help.
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These are two very different trials, the fact that one was done on rats and the other on humans is really inconsequential. What is important is that one was done on rats who had been induced IBD by contrast the other study was healthy individuals. The test done on humans was only testing the safety of Manuka honey, whereas the tests done on the rats was measuring colonic inflammation.
I wonder on the amounts given to the rats if that was over the entire course of the trial. On a 30kg dog this would average about 17g/day, which is between 2 tsps and 1 Tbsp per day.
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My girls T4 is .2, after a complete Thyroid workup at Michigan State it revealed that she was fine. I would go with the neuro route. A MRI is the only way to know for sure.
I believe that is what she is leaning towards. She's going to speak with her regular vet tomorrow about that.
ETA: Thanks 3greys2cats for the explanation of GME.
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You started a thread early March about bad gas and smelly poops. I wonder if the cause is not the foods but bacteria they have picked up from drinking this water.
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In a quick google, the only human study that I found was at:
http://www.ncbi.nlm.nih.gov/pubmed/20064284
It's a small study .. only 20 people and while they didn't see any benefits, more importantly they didn't see any harmful effects on people.
Not really sure why they would expect to see a reduction in gut bacterial levels in healthy adults.
We all know our digestive system is full of bacteria.
That would indicate to me that it does not interfere with the bacterial balance in healthy adults. (ETA, Afterall isn't this the problem with the use of antiobiotics. They destroy both the bad and good bacteria., which in itself has a negative effect.) To me this speaks more to the benefits and use of Manuka honey.
Here's another human study I found on the effects of Manuka honey for plaque and gingivitis. I know it's totally unrelated to the subject the use of Manuka honey for IBD and colitis, but nevertheless still interesting considering all the problems greyhounds have with their teeth.
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Hoping for an update here too. I hope the problem has been found so he can be treated properly and be started on the road to recovery.
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Is the dog eating something that your friend might not know about? Has the grass been fertilized...are there mushrooms in the yard...toads? My angel, Bailey had head tremors one day and I thought back on what we'd done and remembered that I'd let her eat grass at the park. Obviously I never let her eat grass anywhere but our own backyard after that and she never had them again.
She has thought about that. She said he has been eating a lot of grass, but only in her yard. The only fertilizer she put out was around her flowers and she tries to make sure it gets watered into the ground good. I'll tell her to check for mushrooms in her yard. Don't they usually foam at the mouth if they've tried to eat a toad? If she had gotten into something wouldn't it show up on the bloodwork somehow?
I really appreciate everyone's thoughts and suggestions that they have given.
Doesn't sound minor thyroid issue related to me.
Possibly GME??? -- but that might be a stretch..
Poodle lost balance and stumbled after both his strokes, but never had trembling issues.
I'd vote for a neuro visit as stop #1.
What is GME?
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Two thumbs plus also 4 paws up for Manuka honey from this house.
Buzzy
Buzzy, we're wondering where you get your supply!
Specifically what brand is it and did yours have the UMF rating?
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Thanks Jey, I'll let her know this.
Rickiesmom I will definitely let her know about MSU. Thanks for posting that here.
Chicocat she said ear infection was ruled out, not sure how though.
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manawatugal it is raw unpasteurized Manuka honey that I am getting. I'm going to have to check out the Manuka oil. I found a really good article on Manuka honey on the Waikato website.
Where are you getting your supply? Google offers a dizzying array of possibilities!
Well it appears I may need to do more reading. I thought Hi-Active and UMF ratings were the same. Mine have a Hi-Active rating of 16+ and I have had good results with it. I would like to get some though that had the UMF rating. I wonder what kind Buzzy used for Sweetpea.
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If he's currently taking thyroid meds, he needs to be off of those for 6 weeks before doing the full panel.
I would head straight for a neuro, tho. Those are neuro symptoms.
He's only had 2 pills so far. If she stops giving them now would she still need to wait that long.
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That said, it's true that decades ago you could say that most vets pretty much went by what dog food companies would say but, that is not common today especially with vets in large cities that specialize in nutrition and engage in their own research on animal diets or are likely to "pour over" data that dog food companies provide.
By "pour over" do you mean scrutinize or do you mean as a basis for their knowledge. Because quite frankly I don't see a dogfood company providing any data that would reflect positive on raw feeding.
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The loss of BALANCE is not a symptom of mild hypothyroid-
My first thought was vestibular disease--how was this "ruled out"?
I agree with seeing a neurologist.
He's not exhibiting the signs of Vestibular dysfunction. He doesn't have the classic head tilt or wide body stance.
I talked to her not too long ago.She is going to have a full thyroid panel done and also have him checked for tick-borne diseases. She also mentioned taking him to a specialist. I always find it good to arm yourself with questions to ask before you go.
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It is very important that hypothyroidism NOT be diagnosed in a greyhound with just a T4! They need a full thyroid panel. My greyhound had a T4 of 0.4 and her panel revealed her to be perfectly normal.
I think head tremors can be a linked to hypothyroidism, but this vet isn't practicing good greyhound medicine.
I told my friend that this morning that she really needs to have a full thyroid panel done.
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manawatugal it is raw unpasteurized Manuka honey that I am getting. I'm going to have to check out the Manuka oil. I found a really good article on Manuka honey on the Waikato website.
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Vestibular disease was brought up and ruled out. The vet was going with hypothyroidism because of the low number and put him on thyroid pills, but I think more is going on here.
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I need GT's very large collective brain to give me some ideas of what is possibly going on with my friend's greyhound. First of all she has taken him to the vet and a blood panel and urinalysis was done, but nothing was out of range except the T4 which was just a tad low at (.4) which I know is really not enough to go on.
Okay now with his symptoms. He loses his balance when walking. I saw him today and he walks with kind of a staggering gate like he's about to fall over. She said he fell against the wall when taking a small step down. He has lost his appetite along with 7lbs. The strangest thing are the head and neck tremors my friend says she has witnessed twice, body is still but head and neck are shaking very rapidly. Any ideas what this could be or what tests should be run?
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I'm glad to hear that things are looking okay with Fenway and Grace. Sounds like from what others have posted you shouldn't have to worry about any long term bad effects. I had 5 here that got into 4 Comfortis tablets that were for a 120lb dog. Didn't know if 1 dog got them all or several shared them. I called the vet because it was going to be real hard to get all 5 there at one time really not knowing which one(s) really needed to go. The vet instructed me to induce vomiting and to monitor. All turned out well.
).
Irritable Bowel Disease And Ple
in Health and Medical discussion
Posted
Speaking of not hurting, did you read the exhaustive list of very serious side effects caused by Sulfasalazine, a drug prescribed by "modern" medicine for IBD, that is what I found scarey. Now there is an example of "can hurt" for you.