Thoughts and prayers to Dempsey and your family. I had a grey with osteo but chose not to amputate. Its a wicked, evil disease! Chloe lasted about 5 months or so with hospice like care and knew she was loved by all. Another bridge hound had lymphosarcoma and we did go with chemo. He went into remission for over a year! Several GTers have gone through the same thing you are experiencing so I hope they can give you more info. Mimi