I'm new to board and have searched LS extensively. THANK YOU to all who have posted on this board in the past! My almost-14 y.o. boy has lumbosacral stenosis.
Background (you can skip to problems/questions if you want):
For 3 years it's progressed slowly, controlled by glucosamine/chondroitin/MSM/herbal supplements, fish oil and derramax, then metacam. Last six months it has progressed rapidly. Acupuncture helped a little but not much. Chiro didn't seem to help at all, though he liked going. Tramadol did not ever seem to make a difference at the dose prescribed previously (40mg 2x/day). Saw a neuro three weeks ago who said Dune's too old for surgery, so instead we went on prednisone oral 2x/day and 50mg tramadol 2x/day.
Some improvement on pred + tramadol but not much; tramadol at higher dose does seem to help though he's more unsteady and a bit dopey when I first give it. Breaking dose into 4x/day, 25mg each time, seems to keep him somewhat comfortable and still alert. Lots of panting on this regimen, which I understand is normal, though it worries me that it's pain and not normal steroid/tramadol panting, though he otherwise seems okay: eating, following me room to room although it's tough to get up and down.
The problem(s):
1. My boy is hard to pill. I and my vet are the only two who seem able to reliably put a pill down his throat. He is not food motivated and will refuse food that has had a pill snuck into it previously (for two years now he has refused to eat cottage cheese, hot dogs or lunch meat of any kind because a dogsitter tried to pill him that way). I have no choice but leave him in the care of his beloved dog-godparents for three weeks soon, and even though they can pill their own dogs, they've never been able to pill him. I need a non-pill way to give tramadol and steroids.
2. My neuro and vet both say the depo-medrol injections have no more effect than oral or other injectable steroids and it's not a magic pill. They are loathe to try it because it is a long-acting steroid and if he has a reaction, we can't undo it. They both said that the Depo-Medrol injection is "an old wives' tale" without any studies showing efficacy (beyond what you'd see with oral prednisone). They also say there are serious side effects and it's considered "quackery" now to use it in dogs. My regular vet is willing to try it for me if I insist, though. It's up to me on Monday afternoon. I am leaning toward trying it, mainly because of problem #1 -- this will reduce the number of pills the dogsitters must get in him.
My question:
Does anyone know of any validated research on both the efficacy of depo medrol for LS and the side effects?
Does anyone know of a way to give tramadol in a liquid form from a syringe, and is this easier for people than pilling?
Does anyone have other suggestions?