Greysworld Posted February 15, 2022 Share Posted February 15, 2022 Wondering what dosage of Keppra extended release other greyhounds are on. My vet would like to switch our 11yr old seizure boy from Phenobarb to Keppra. She's recommending 500mg + 750mg, which sounds like a lot. Quote Link to comment Share on other sites More sharing options...
greysmom Posted February 16, 2022 Share Posted February 16, 2022 General recommendations are 5-10 mg per pound, given three times a day (or twice a day for extended release). So a 70 lb dog would be 700 mg x 3. What your vet is recommending is lower than the recommended dosage. But, I would definitely consider switching. Phenobarb can be a hard drug on many dogs, with lots of side effects and needing lots of bloodwork and monitoring. Keppra is generally well tolerated, with few side effects except a little initial sedation. It's usually given along with pheno, at least at the beginning, and then the pheno is tapered off as low as possible (or completely withdrawn if the dog doesn't need it to keep the seizures controlled). Quote Chris - Mom to: Felicity (DeLand), and Andi (Braska Pandora) siggy by Chris Harper, on Flickr Angels: Libby (Everlast), Dorie (Dog Gone Holly), Dude (TNJ VooDoo), Copper (Kid's Copper), Cash (GSI Payncash), Toni (LPH Cry Baby), Whiskey (KT's Phys Ed), Atom, Lilly Link to comment Share on other sites More sharing options...
Greysworld Posted February 16, 2022 Author Share Posted February 16, 2022 Great, thank you! Quote Link to comment Share on other sites More sharing options...
tbhounds Posted February 18, 2022 Share Posted February 18, 2022 Why switch? Pheno is tried and true….if it’s not broke don’t fix it. You may see breakthroughs seizures while transitioning. If the pheno is causing elevated liver enzyme’s inquire about using Denamarin concurrently. Quote Link to comment Share on other sites More sharing options...
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