4My2Greys Posted July 7, 2012 Share Posted July 7, 2012 With Bruiser's recent diagnosis of hemangiosarcoma I have been reading everything I can with regards to supplements that could help in his treatment. I found the following articles and studies to be very interesting regarding melatonin. http://www.canceractive.com/cancer-active-page-link.aspx?n=1242& Title=Melatonin%20and%20cancer%20prevention Melatonin, sleep disturbance and cancer risk. http://www.ncbi.nlm.nih.gov/m/pubmed/19095474/ Research: Melatonin-chemotherapy improves survival from cancer http://m.digitaljournal.com/article/324927 Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumor patients with poor clinical status http://www.ncbi.nlm.nih/gov/m/pubmed/10674014 Melatonin potentiates chemotherapy-induced cytotoxicity and aptosis in rat pancreatic tumor cells http://onlinelibrary.wiley.com/doi/10.1111/j.1600-079X.2012.00974.x/abstract Quote Link to comment Share on other sites More sharing options...
TwiggysMom Posted July 7, 2012 Share Posted July 7, 2012 These were interesting articles, thanks for posting them. I think I'll ask the integrative care vet about these at Twiggy's consult next week, as well as her oncologist. It sounds like it might be worth trying (even though she's only on cytoxan now). I'm also interested in curcumin, and want to see what they think about that too. From the human side, I found the link between lack of sleep at night and breast cancer interesting. My mother had breast cancer years ago, and she has never liked to sleep at night. She says her clock is just backwards. I wonder whether there is some connection (she was pretty young when she had it). Quote Wendy with Twiggy, fosterless while Twiggy's fighting the good fight, and Donnie & Aiden the kitties Link to comment Share on other sites More sharing options...
4My2Greys Posted July 8, 2012 Author Share Posted July 8, 2012 These were interesting articles, thanks for posting them. I think I'll ask the integrative care vet about these at Twiggy's consult next week, as well as her oncologist. It sounds like it might be worth trying (even though she's only on cytoxan now). I'm also interested in curcumin, and want to see what they think about that too. From the human side, I found the link between lack of sleep at night and breast cancer interesting. My mother had breast cancer years ago, and she has never liked to sleep at night. She says her clock is just backwards. I wonder whether there is some connection (she was pretty young when she had it). Wendy, something else you might be interested in is the study of chronobiology and circadian rhythms in the dosing times of chemo drugs. There has been show to be as much as a 50% difference in side effects and tumor kill ratio depending on the time of day each drug was administered. Quote Link to comment Share on other sites More sharing options...
Guest 2dogs4cats Posted July 8, 2012 Share Posted July 8, 2012 Look into Astralagus. Quote Link to comment Share on other sites More sharing options...
4My2Greys Posted July 8, 2012 Author Share Posted July 8, 2012 2dogs4cats, thank you for posting that. I will definitely be adding that to Bruiser's regimen. Here's more info if anyone is interested. http://www.canceractive.com/cancer-active-page-link.aspx?n=536 Quote Link to comment Share on other sites More sharing options...
TwiggysMom Posted July 9, 2012 Share Posted July 9, 2012 These were interesting articles, thanks for posting them. I think I'll ask the integrative care vet about these at Twiggy's consult next week, as well as her oncologist. It sounds like it might be worth trying (even though she's only on cytoxan now). I'm also interested in curcumin, and want to see what they think about that too. From the human side, I found the link between lack of sleep at night and breast cancer interesting. My mother had breast cancer years ago, and she has never liked to sleep at night. She says her clock is just backwards. I wonder whether there is some connection (she was pretty young when she had it). Wendy, something else you might be interested in is the study of chronobiology and circadian rhythms in the dosing times of chemo drugs. There has been show to be as much as a 50% difference in side effects and tumor kill ratio depending on the time of day each drug was administered. Definitely need to look into that. Twiggy has been having more than typical side effects from her oral chemo (may or may not be related to her bad reaction to her last iv chemo - that seemed to kick things off, though). Thanks for that thought!!! Quote Wendy with Twiggy, fosterless while Twiggy's fighting the good fight, and Donnie & Aiden the kitties Link to comment Share on other sites More sharing options...
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