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Melatonin And Cancer Prevention/treatment


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With Bruiser's recent diagnosis of hemangiosarcoma I have been reading everything I can with regards to supplements that could help in his treatment. I found the following articles and studies to be very interesting regarding melatonin.

 

http://www.canceractive.com/cancer-active-page-link.aspx?n=1242& Title=Melatonin%20and%20cancer%20prevention

 

Melatonin, sleep disturbance and cancer risk.

 

http://www.ncbi.nlm.nih.gov/m/pubmed/19095474/

 

Research: Melatonin-chemotherapy improves survival from cancer

 

http://m.digitaljournal.com/article/324927

 

Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumor patients with poor clinical status

 

http://www.ncbi.nlm.nih/gov/m/pubmed/10674014

 

Melatonin potentiates chemotherapy-induced cytotoxicity and aptosis in rat pancreatic tumor cells

 

http://onlinelibrary.wiley.com/doi/10.1111/j.1600-079X.2012.00974.x/abstract

 

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These were interesting articles, thanks for posting them.

 

I think I'll ask the integrative care vet about these at Twiggy's consult next week, as well as her oncologist. It sounds like it might be worth trying (even though she's only on cytoxan now). I'm also interested in curcumin, and want to see what they think about that too.

 

From the human side, I found the link between lack of sleep at night and breast cancer interesting. My mother had breast cancer years ago, and she has never liked to sleep at night. She says her clock is just backwards. I wonder whether there is some connection (she was pretty young when she had it).

Wendy with Twiggy, fosterless while Twiggy's fighting the good fight, and Donnie & Aiden the kitties

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These were interesting articles, thanks for posting them.

 

I think I'll ask the integrative care vet about these at Twiggy's consult next week, as well as her oncologist. It sounds like it might be worth trying (even though she's only on cytoxan now). I'm also interested in curcumin, and want to see what they think about that too.

 

From the human side, I found the link between lack of sleep at night and breast cancer interesting. My mother had breast cancer years ago, and she has never liked to sleep at night. She says her clock is just backwards. I wonder whether there is some connection (she was pretty young when she had it).

 

Wendy, something else you might be interested in is the study of chronobiology and circadian rhythms in the dosing times of chemo drugs. There has been show to be as much as a 50% difference in side effects and tumor kill ratio depending on the time of day each drug was administered.

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These were interesting articles, thanks for posting them.

 

I think I'll ask the integrative care vet about these at Twiggy's consult next week, as well as her oncologist. It sounds like it might be worth trying (even though she's only on cytoxan now). I'm also interested in curcumin, and want to see what they think about that too.

 

From the human side, I found the link between lack of sleep at night and breast cancer interesting. My mother had breast cancer years ago, and she has never liked to sleep at night. She says her clock is just backwards. I wonder whether there is some connection (she was pretty young when she had it).

 

Wendy, something else you might be interested in is the study of chronobiology and circadian rhythms in the dosing times of chemo drugs. There has been show to be as much as a 50% difference in side effects and tumor kill ratio depending on the time of day each drug was administered.

 

Definitely need to look into that. Twiggy has been having more than typical side effects from her oral chemo (may or may not be related to her bad reaction to her last iv chemo - that seemed to kick things off, though).

 

Thanks for that thought!!!

Wendy with Twiggy, fosterless while Twiggy's fighting the good fight, and Donnie & Aiden the kitties

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