Wonder Posted November 4, 2010 Share Posted November 4, 2010 I can't find my answer on Dr Stack's site so anyone know what the range for a hound for ALT is? thanks Quote Kari and the pups.Run free sweet Hana 9/21/08-9/12/10. Missing Sparks with every breath.Passion 10/16/02-5/25/17 Link to comment Share on other sites More sharing options...
turbotaina Posted November 4, 2010 Share Posted November 4, 2010 Greyhounds are not abnormal when it comes to ALT. I may be able to find the values... On Turbo's last bloodwork, the normal reference range is 12-118 U/L Quote Meredith with Heyokha (HUS Me Teddy) and Crow (Mike Milbury). Missing Turbo (Sendahl Boss), Pancho, JoJo, and "Fat Stacks" Juana, the psycho kitty. Canku wakan kin manipi."Those who can make you believe absurdities can make you commit atrocities." - Voltaire Link to comment Share on other sites More sharing options...
NeylasMom Posted November 4, 2010 Share Posted November 4, 2010 I can't find my answer on Dr Stack's site so anyone know what the range for a hound for ALT is? thanks Funny, I just got Neyla's blook work back and the ALT level is the only thing that's really out of range (on the high side) for her. I think the normal ranges depend on the lab, but from what I can tell looking at this and previous blood work, it's around 5-118. Anyone know what a high ALT indicates? I haven't researched yet b/c they had a problem with their machine and I'm waiting for the actual results to come back from the lab. These results show hemolysis, which can affect ALT levels apparently. Quote Jen, CPDT-KA with Zuri, lab in a greyhound suit, Violet, formerly known as Faith, Skye, the permanent puppy, Cisco, resident cat, and my baby girl Neyla, forever in my heart "The great thing about science is that you're free to disagree with it, but you'll be wrong." Link to comment Share on other sites More sharing options...
turbotaina Posted November 4, 2010 Share Posted November 4, 2010 This is from the OSU site: <H3>Liver enzymesThe liver enzymes alanine transaminase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) are all used to evaluate the health of the liver and can be increased in association with various liver diseases. ALT is an enzyme found inside hepatocytes (liver cells) and in muscle fibers; damage to hepatocytes or muscle by toxins, trauma, or inflammation causes increases in ALT activity (values) in serum. As a general rule, high ALT activity is suggestive of ongoing liver damage (of which there are many causes, such as hepatitis and ingestion of toxins or drugs); however, trauma (e.g. a dog hit by a car) or extensive muscle damage (e.g. rhabdomyolysis) can cause increases in ALT activities. AST is less liver- specific than ALT; high AST activity usually occurs in cases of severe muscle or liver damage, in addition to liver disease. In most dogs with extensive muscle disease, another enzyme (CK or creatinine kinase) is also markedly increased in serum. Greyhounds have slightly higher ALT, AST, and CK activities than non-Greyhound dogs. ALP is less liver-specific than ALT. When increases in ALP are due to liver disease, the bile pigment (bilirubin) concentration also increases, and the dog may be jaundiced (yellow). ALP activity can also be mildly increased in young growing dogs, and markedly increased in association with reactions to certain drugs (corticosteroids, barbiturates) or adrenal gland disease (hyperadrenocorticism or Cushing’s disease). Additional information on the liver can be gained by evaluating the cholesterol, albumin, BUN, and bilirubin concentrations. Decreased concentrations of cholesterol, BUN, and/or albumin (see below), and increased concentration of bilirubin can be seen in dogs with some types of chronic liver disease. Changes in some or several of these values may be an indication for your veterinarian to assess liver function or morphology. A bile acid blood test before and after feeding is one of the tests used to evaluate liver function, and is normally not included in a standard biochemical profile; abdominal radiographs and ultrasonography are noninvasive techniques used to image the liver. </H3> Quote Meredith with Heyokha (HUS Me Teddy) and Crow (Mike Milbury). Missing Turbo (Sendahl Boss), Pancho, JoJo, and "Fat Stacks" Juana, the psycho kitty. Canku wakan kin manipi."Those who can make you believe absurdities can make you commit atrocities." - Voltaire Link to comment Share on other sites More sharing options...
Wonder Posted November 4, 2010 Author Share Posted November 4, 2010 (edited) I did a quick search and hounds have a higher ALT than other dogs (isn't that almost the case with other stuff on blood work??) I found this but didn't see a range listed http://www.greyhound..._Greyhounds.pdf Edited November 4, 2010 by Wonder Quote Kari and the pups.Run free sweet Hana 9/21/08-9/12/10. Missing Sparks with every breath.Passion 10/16/02-5/25/17 Link to comment Share on other sites More sharing options...
turbotaina Posted November 4, 2010 Share Posted November 4, 2010 Hm. Looks like slightly higher values are not out of the ordinary. Quote Meredith with Heyokha (HUS Me Teddy) and Crow (Mike Milbury). Missing Turbo (Sendahl Boss), Pancho, JoJo, and "Fat Stacks" Juana, the psycho kitty. Canku wakan kin manipi."Those who can make you believe absurdities can make you commit atrocities." - Voltaire Link to comment Share on other sites More sharing options...
Wonder Posted November 4, 2010 Author Share Posted November 4, 2010 Hm. Looks like slightly higher values are not out of the ordinary. I still can't find anything listing a range though Quote Kari and the pups.Run free sweet Hana 9/21/08-9/12/10. Missing Sparks with every breath.Passion 10/16/02-5/25/17 Link to comment Share on other sites More sharing options...
NeylasMom Posted November 4, 2010 Share Posted November 4, 2010 I doublechecked and these are the for real results. Neyla's ALT is significantly increased and her AST is up a bit. Looks like we may be looking at liver issues. Time to send this off to our oncologist. Hm. Looks like slightly higher values are not out of the ordinary. I still can't find anything listing a range though Did you see my post? Idexx range is 5-107, Antech is 12-118, close enough that I think you can use those for comparison. But check for notes on hydrolysis as my lab work says it can cause an increased value as well. Quote Jen, CPDT-KA with Zuri, lab in a greyhound suit, Violet, formerly known as Faith, Skye, the permanent puppy, Cisco, resident cat, and my baby girl Neyla, forever in my heart "The great thing about science is that you're free to disagree with it, but you'll be wrong." Link to comment Share on other sites More sharing options...
Wonder Posted November 4, 2010 Author Share Posted November 4, 2010 I doublechecked and these are the for real results. Neyla's ALT is significantly increased and her AST is up a bit. Looks like we may be looking at liver issues. Time to send this off to our oncologist. Hm. Looks like slightly higher values are not out of the ordinary. I still can't find anything listing a range though Did you see my post? Idexx range is 5-107, Antech is 12-118, close enough that I think you can use those for comparison. But check for notes on hydrolysis as my lab work says it can cause an increased value as well. Yeah, I saw your post but for some reason was thinking those were for normal dogs Couldn't the increase be due to the meds she's taking? Time for milk thistle? Quote Kari and the pups.Run free sweet Hana 9/21/08-9/12/10. Missing Sparks with every breath.Passion 10/16/02-5/25/17 Link to comment Share on other sites More sharing options...
NeylasMom Posted November 4, 2010 Share Posted November 4, 2010 Yeah, I saw your post but for some reason was thinking those were for normal dogs Couldn't the increase be due to the meds she's taking? Time for milk thistle? Yeah, they are for normal dogs. Sorry, you meant for a greyhound, my bad. Still, the link from Meredith notes only slightly increased. Yeah, most likely from the Deramaxx. Not unexpected I guess, just kind of upsetting b/c we were looking for kidney issues all along, I just assumed her liver would be fine. Anyway, yes, we were considering adding milk thistle anyway so I definitely will. For all I know, this level isn't alarming, but it's much higher than her previous blood work and no longer in the normal range so I think it's fishy. Anyway, sorry for the hijack here. Quote Jen, CPDT-KA with Zuri, lab in a greyhound suit, Violet, formerly known as Faith, Skye, the permanent puppy, Cisco, resident cat, and my baby girl Neyla, forever in my heart "The great thing about science is that you're free to disagree with it, but you'll be wrong." Link to comment Share on other sites More sharing options...
Wonder Posted November 4, 2010 Author Share Posted November 4, 2010 Yeah, I saw your post but for some reason was thinking those were for normal dogs Couldn't the increase be due to the meds she's taking? Time for milk thistle? Yeah, they are for normal dogs. Sorry, you meant for a greyhound, my bad. Still, the link from Meredith notes only slightly increased. Yeah, most likely from the Deramaxx. Not unexpected I guess, just kind of upsetting b/c we were looking for kidney issues all along, I just assumed her liver would be fine. Anyway, yes, we were considering adding milk thistle anyway so I definitely will. For all I know, this level isn't alarming, but it's much higher than her previous blood work and no longer in the normal range so I think it's fishy. Anyway, sorry for the hijack here. hijack away I'm just asking for someone in my group and my vet is out of the country so I can't call him to ask Quote Kari and the pups.Run free sweet Hana 9/21/08-9/12/10. Missing Sparks with every breath.Passion 10/16/02-5/25/17 Link to comment Share on other sites More sharing options...
Guest esandy Posted November 10, 2010 Share Posted November 10, 2010 Hello, I just found out that Gracie's ALT scores are high too, so I'm interested in hearing from anyone else who has been through this what it might be. The vet suggested that since she is in good health otherwise, we try giving her some 'nutro-ceuticals' for a few weeks then retest the ALT result to see if it improves. Has anyone else had experience with a high ALT score? Thanks! Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You can post now and register later. If you have an account, sign in now to post with your account.