kudzu Posted July 27, 2011 Share Posted July 27, 2011 Has anyone heard of Incurin? It is a newly approved drug to treat spay incontinence. Here's the link FDA article. It says Incurin is estriol. Am just wondering what the difference is between this & DES, besides all the money & studies that went behind getting it patented & FDA approved. Also wondering how much price difference there will be between it & DES. No probs with spay incontinence here but know enough folks with dogs who have had it. Quote Link to comment Share on other sites More sharing options...
JJNg Posted July 31, 2011 Share Posted July 31, 2011 While there doesn't seem to be much info about Incurin in the US, it appears that it's been used for spay incontinence in Europe for a while. From what I've been able to find, it is a shorter acting estrogen compound, so has to be dosed more frequently than DES. Starting dose is daily with both. But with DES, you can often get down to every 5-7 days, while with Incurin, it usually needs to be given at least every 2-3 days. However, Incurin may be a bit safer, with less potential for bone marrow suppression (which is very rare but can happen with higher doses of DES). I imagine Incurin will probably be more expensive since it's a brand name product actually labeled and approved for this use. There are no commercial DES products, so it is only available through compounding pharmacies. Quote Jennifer & Willow (Wilma Waggle), Wiki (Wiki Hard Ten), Carter (Let's Get It On), Ollie (whippet), Gracie (whippet x), & Terra (whippet) + Just Saying + Just Alice Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You can post now and register later. If you have an account, sign in now to post with your account.