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Hypothetical Tbd/tick Panel Question


Guest argolola

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Guest argolola

Rudy has been though every test known to man, it seems. The doctors were stumped when the tick panel came back negative.

 

He was first put on a 3 week course of Doxy. Two days later the fever came back and he started another 4 week round of Doxy a week later with a new vet.

 

The good news is that after finishing his last round, a week and a half later his fever has not been over 101.5!!!

 

Is it possible for Doxy to have treated the TBD, thus the panel coming back negative?

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Guest argolola

I'm not sure, because I didn't see the results, but I think they said it tested 11 different strains. He is doing so well, I am just waiting to exhale.

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If he started on antibiotics before the blood draw that was sent for testing, then that could certainly have had an effect.

Star aka Starz Ovation (Ronco x Oneco Maggie*, litter #48538), Coco aka Low Key (Kiowa Mon Manny x Party Hardy, litter # 59881), and mom in Illinois
We miss Reko Batman (Trouper Zeke x Marque Louisiana), 11/15/95-6/29/06, Rocco the thistledown whippet, 04/29/93-10/14/08, Reko Zema (Mo Kick x Reko Princess), 8/16/98-4/18/10, the most beautiful girl in the whole USA, my good egg Joseph aka Won by a Nose (Oneco Cufflink x Buy Back), 09/22/2003-03/01/2013, and our gentle sweet Gidget (Digitizer, Dodgem by Design x Sobe Mulberry), 1/29/2006-11/22/2014, gone much too soon. Never forgetting CJC's Buckshot, 1/2/07-10/25/10.

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Guest argolola

He is doing so well now. He's so full of life and excited about things, but still a bit shy. He must have been feeling so bad or traumatized with the fever because his dark snout started turning white in 2 months time.

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Supposedly starting doxy will not affect the erlichia test. Also, Dr. Stack says that they may test negative if they are in a full blown infection (those are not her words--I'll try & find them)

 

Yes - the panels test positive or negative by identifying the dog's antibodies against the disease. However, if the dog is very sick, it dog may not be creating an immune response at all so that the antibodies would not be found on the test. I would think that you could only us a PCR test in that case (and I believe the only PCR test is for babesiosis alone).

 

And Diane, as Dr. Couto said in the seminar we were at at SP last year - "It's not the diseases we know about, it's about the ones we don't". So, Lene, there absolutely could be TBDs out there that we don't even know about and so can't test for.


Meredith with Heyokha (HUS Me Teddy) and Crow (Mike Milbury). Missing Turbo (Sendahl Boss), Pancho, JoJo, and "Fat Stacks" Juana, the psycho kitty. Canku wakan kin manipi.

"Those who can make you believe absurdities can make you commit atrocities." - Voltaire

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(and I believe the only PCR test is for babesiosis alone).

 

No, there are PCRs for all kinds of things, including all the ehrlichias.

 

If treatment with doxy can lower a dog's antibodies, then starting doxy certainly could affect test results. If it couldn't, then we wouldn't see reduced titers on retest. Would it have an effect on the titer within days? Dunno about that. But IIRC, Lene's pup had a course of doxy before he was tested and then put on doxy again.

 

Other possibilities include: He was tested early in the disease course, before he'd formed antibodies. Or he had/has something other than tick disease. There are lots of infectious processes that will produce similar symptoms; very few symptoms cited for tick disease are unique to tick disease.

Edited by Batmom

Star aka Starz Ovation (Ronco x Oneco Maggie*, litter #48538), Coco aka Low Key (Kiowa Mon Manny x Party Hardy, litter # 59881), and mom in Illinois
We miss Reko Batman (Trouper Zeke x Marque Louisiana), 11/15/95-6/29/06, Rocco the thistledown whippet, 04/29/93-10/14/08, Reko Zema (Mo Kick x Reko Princess), 8/16/98-4/18/10, the most beautiful girl in the whole USA, my good egg Joseph aka Won by a Nose (Oneco Cufflink x Buy Back), 09/22/2003-03/01/2013, and our gentle sweet Gidget (Digitizer, Dodgem by Design x Sobe Mulberry), 1/29/2006-11/22/2014, gone much too soon. Never forgetting CJC's Buckshot, 1/2/07-10/25/10.

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I think it takes a while for titers to come down after treatment, like several months or more. It's because the titer isn't testing for the actual disease, but rather the body's response to the disease, the antibodies, and those take a while to decrease after the disease is gone.

 

I look at TBD titers kind of like I look at fecals, but much more seriously, of course. If something is found, then the dog has it, but if nothing is found, that does not necessarily mean the dog is good to go.

 

The numbers of the titers are also revealing. A lab or vet may call a titer negative, when it was actually a very low positive. In my mind, a negative is zero.

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(and I believe the only PCR test is for babesiosis alone).

 

No, there are PCRs for all kinds of things, including all the ehrlichias.

 

 

Ah! NC State has a new form - I see all the PCRs now. Good to know!

 

In case you need it, Lene:

 

NCSU TBD Panel Request Form


Meredith with Heyokha (HUS Me Teddy) and Crow (Mike Milbury). Missing Turbo (Sendahl Boss), Pancho, JoJo, and "Fat Stacks" Juana, the psycho kitty. Canku wakan kin manipi.

"Those who can make you believe absurdities can make you commit atrocities." - Voltaire

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