win4profit Posted November 21, 2015 Share Posted November 21, 2015 Friday morning at 3:30 am I awoke to Slick bumping into the dresser, he then comes over and bumps into the bed. I get up immediately because he is also panting, I thought maybe he was going to be sick. Once my eyes were focused, I could see he was swaying as if he were drunk. His rear legs were splayed wide apart and his head was down and he was very unstable. I knelt down to give him balance and called out for my DH. Diamond, being all puppy, thought it was time to get up and go out. DH went to let her out while I continued to tend to Slick. He tried to take two steps and then melted to the floor. He is panting and drooling and shaking. While DH goes out to start the van to take him to the evet, Slick pukes about a mouthful of kibble. We get this cleaned up and Diamond back inside and DH carries him to the van. I called ahead to let them know we would need help to get him in since DH hurt his back carrying him out. They met us at the door and we got him on the cart and they took him back immediately. We gave them all the details including the fact that we started him on Bravecto earlier that night. About a half an hour later, the Dr. came out to tell us that he was standing on his own and taking small steps. She told us his pupils were dilated and slow to respond and gently asked us if he could have gotten into any marijuana. Granted, after falling out of bed at 3:30 in the morning and throwing on the first thing, we probably looked the part but we assured her that there was no way. We agreed to check the yard for anything that he could have gotten into. We also agreed to leave him there so they could monitor him for any other episodes. They did a full CBC profile and found it was unremarkable. He did not have any further episodes and we brought him home around 5:30. He ate well and slept through the night. Today, he seems to be his old self. I spoke to my vet and she is adamant that it was not the Bravecto that initiated this episode. She did contact the drug rep to report it and was told that there were no other issues of neurologic episodes reported. She believes that he may have had seizure and I only woke to see the aftermath. I am sleeping very light because of Diamond being so new and do not believe that I would have slept through a seizure. So, does anybody have any ideas what this was? Quote Link to comment Share on other sites More sharing options...
macoduck Posted November 21, 2015 Share Posted November 21, 2015 The onset behavior sounds like a vestibular episode. It eventually passes but can recur in the future. Quote NoAh the podenco orito, Rita the podenco maneta, Howie the portuguese podengo maneto Angels: Mr X aka Denali, Lulu the podenco andaluz, Hada the podenco maneta, Georgie Girl (UMR Cordella), Charlie the iggy, Mazy (CBR Crazy Girl), Potato, my mystery ibizan girl, Allen (M's Pretty Boy), Percy (Fast But True), Mikey (Doray's Patuti), Pudge le mutt, Tessa the iggy, Possum (Apostle), Gracie (Dusty Lady), Harold (Slatex Harold), "Cousin" Simon our step-iggy, Little Dude the iggy ,Bandit (Bb Blue Jay), Niña the galgo, Wally (Allen Hogg), Thane (Pog Mo Thoine), Oliver (JJ Special Agent), Comet, & Rosie our original mutt. Link to comment Share on other sites More sharing options...
Burpdog Posted November 21, 2015 Share Posted November 21, 2015 (edited) Why won't vets blame meds when they are to blame??? Bravecto™ may interact with other medications. Consult with your veterinarian to discuss using other medications when your pet is on Bravecto™. Bravecto™ is an oral agent. The most common side effects noted were vomiting, decreased appetite, diarrhea, lethargy, drinking more and gas (flatulence). Product is not approved for use in cats. Read more at: https://tr.im/tPTdl http://www.petplace.com/article/drug-library/library/prescription/fluralaner-bravecto http://www.merck-animal-health-usa.com/news/2014-5-20.aspx Notice the control test group is ONLY 224 dogs. Edited November 21, 2015 by Burpdog Quote Diane & The Senior Gang Burpdog Biscuits Link to comment Share on other sites More sharing options...
racindog Posted November 21, 2015 Share Posted November 21, 2015 Why won't vets blame meds when they are to blame??? Bravecto™ may interact with other medications. Consult with your veterinarian to discuss using other medications when your pet is on Bravecto™. Bravecto™ is an oral agent. The most common side effects noted were vomiting, decreased appetite, diarrhea, lethargy, drinking more and gas (flatulence). Product is not approved for use in cats. Read more at: https://tr.im/tPTdl http://www.petplace.com/article/drug-library/library/prescription/fluralaner-bravecto http://www.merck-animal-health-usa.com/news/2014-5-20.aspx Notice the control test group is ONLY 224 dogs. Ditto. Could it be more obvious? He was fine until he got exposed to it. Those kind of meds are far far from innocuous. Like Dr. Cuoto says- anytime you give a greyhound a new med it is an adventure. You never know how they may react to it. JMO. Quote Link to comment Share on other sites More sharing options...
3greytjoys Posted November 21, 2015 Share Posted November 21, 2015 I agree that Greyhounds of any age are more sensitive to many drugs than other breeds. I don't recall Slick's current age, but hounds can become even more drug sensitive as they age. One example (of several): One of our 13 year old hounds recently spent weeks trying to recover from two separate medication reactions. The most surprising was a simple (vet recommended) dose of Pepcid. (Over the years on an "as needed" basis, 10 mg. of Pepcid has worked well for all of our Greyhounds. This time, vet prescribed a (general breed) dose of 20 mg. which was too much for his system.) We've never used Bravecto. The only flea+tick treatment we've ever used on our younger hounds (or fosters) is topical Frontline. Glad Slick seems to be recovering well. Quote Link to comment Share on other sites More sharing options...
Houndtime Posted November 21, 2015 Share Posted November 21, 2015 Our original greyhound group director always said, if it is not safe for cats, it is not safe for greyhounds. Quote Irene Ullmann w/Flying Odin in Lower Delaware Angels Brandy, John E, American Idol, Paul, Fuzzy and Shine Handcrafted Greyhound and Custom Clocks http://www.houndtime.com Zoom Doggies-Racing Coats for Racing Greyhounds Link to comment Share on other sites More sharing options...
MaryJane Posted November 21, 2015 Share Posted November 21, 2015 It sounds like it was a seizure and it was probably caused by the Bravecto. Flea & tick meds are known to trigger seizures. Quote Link to comment Share on other sites More sharing options...
3greytjoys Posted November 22, 2015 Share Posted November 22, 2015 Just wanted to add that some other symptoms of toxicity/poisoning (depending on the type of toxin) are: Vomiting Hypersalivation Dizziness Lack of coordination Weakness Tremors Seizures Collapsing Paralysis Potential organ failure Death Quote Link to comment Share on other sites More sharing options...
win4profit Posted November 22, 2015 Author Share Posted November 22, 2015 Yeah, I definitely will not be giving him another dose of Bravecto no matter the reassurances from my vet. I just won't take the chance. As a side, Diamond took a dose at the same time and she has shown no affects. Quote Link to comment Share on other sites More sharing options...
kudzu Posted November 22, 2015 Share Posted November 22, 2015 You know the saying, correlation does not imply causation. It is understandable to suspect Bravecto. Will admit that in your position I probably wouldn't have the nerve try it again for a good while, if ever. At this point though, there is no reasonable way to conclude Bravecto was the cause of the problem. Glad Slick has recovered. Hopefully this situation was a one off & never, ever repeats. Seizures & seizure like events can be terribly frightening. No one wants to see a loved one go through that. Quote Link to comment Share on other sites More sharing options...
EllenEveBaz Posted November 22, 2015 Share Posted November 22, 2015 No ideas, just sending ear scritches to Slick and hugs to his humans. Quote Ellen, with brindle Milo and the blonde ballerina, Gelsey remembering Eve, Baz, Scout, Romie, Nutmeg, and Jeter Link to comment Share on other sites More sharing options...
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