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Myesthenia Gravis Or Coonhound Paralysis- Experiences?


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One of our human GTers has had myesthenia gravis. She doesn't post often. Is your question regarding your dog or a person?

 

Hada the podenco maneta, Georgie Girl (UMR Cordella), Lulu the podenco andaluz, Rita the podenco maneta
Angels: Charlie the iggy,  Mazy (CBR Crazy Girl), Potato, my mystery ibizan girl, Allen (M's Pretty Boy), Percy (Fast But True), Mikey (Doray's Patuti), Pudge le mutt, Tessa the iggy, Possum (Apostle), Gracie (Dusty Lady), Harold (Slatex Harold), "Cousin" Simon our step-iggy, Little Dude the iggy ,Bandit (Bb Blue Jay), Niña the galgo, Wally (Allen Hogg), Thane (Pog Mo Thoine), Oliver (JJ Special Agent), Comet, & Rosie our original mutt.

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I know of both but have no direct experience with either, though I did have a dog with a different lower motor neuron disease who was treated with pyridostigmine (Mestinon) which is one of the main drugs used to treat the symptoms of myasthenia gravis. Coonhound paralysis & myasthenia gravis are two different diseases. My understanding is that Coonhound paralysis is like a canine version of Guillain-Barré Syndrome & tends to show up after an infection. It's a polyneuropathy, a disease of multiple nerves. It's an acquired disease that damages the nerves themselves.

 

Myasthenia gravis is a junctionopathy, a disease of the neuromuscular junction. It's usually an autoimmune disease. Sometimes it's mild, but other times it can be quite extreme. After resting a while dogs may seem quite normal but after any exertion or exercise they display varying degrees of weakness. Some polyneuropathies present with similar symptoms but I believe EMG/NCV testing can help differentiate a polyneuropathy from myasthenia gravis. I believe myasthenia gravis in dogs is often treated with immunosupressive drugs. Pyridostigmine is used for symptomatic treatment, depending on symptoms & severity.

 

I hope your dog doesn't have either of these diseases. However, I know from experience that sometimes it's better to at least have a diagnosis rather than wondering what the heck is going on.

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Gamo has been admitted to Tufts and it is suspected he has Coonhound paralysis. It seems the understanding of the disease is evolving. They say it is autoimmune. But what causes the switch to flip is unknown, although there are several believed causes. THey were also looking at MG but his tests last night are indicating CP and we may have diagnosis this morning. It has been hell.

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I have no knowledge of either disease, but wanted to let you know that we are thinking of you and Gamo and hope that he gets better.

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Cindy with Miss Fancypants, Paris Bueller, Zeke, and Angus 
Dante (Dg's Boyd), Zoe (In a While), Brady (Devilish Effect), Goose (BG Shotgun), Maverick (BG ShoMe), Maggie (All Trades Jax), Sherman (LNB Herman Bad) and Indy (BYB whippet) forever in my heart
The flame that burns the brightest, burns the fastest and leaves the biggest shadow

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Good thoughts for Gamo. I don't know anything about the disease and hope you can obtain a diagnosis quickly.

Kyle with Stewie ('Super C Ledoux, Super C Sampson x Sing It Blondie) and forever missing my three angels, Jack ('Roy Jack', Greys Flambeau x Miss Cobblepot) and Charlie ('CTR Midas Touch', Leo's Midas x Hallo Argentina) and Shelby ('Shari's Hooty', Flying Viper x Shari Carusi) running free across the bridge.

Gus an coinnich sinn a'rithist my boys and little girl.

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Please add my good thoughts for your sweet Gamo. :grouphug

Cynthia, & Cristiano, galgo
Always in my heart: Frostman
Newdawn Frost, Keno Jet Action & Chloe (NGA racing name unknown), Irys (galgo), Hannah (weim), Cruz (galgo), & Carly CW Your Charming

Princess http://www.greyhound-data.com/d?i=1018857

"It came to me that every time I lose a dog they take a piece of my heart with them. And every new dog who comes into my life, gifts me with a piece of their heart. If I live long enough, all the components of my heart will be dog, and I will become as generous and loving as they are." -- Unknown

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