greymatters Posted March 6, 2012 Share Posted March 6, 2012 I have a couple of questions for those of you with experience in giving fluoxetine (Prozac) to your hounds. We started our 4 y.o. boy on this about 2 weeks ago, in order to help work through some behavioral issues stemming from anxiety and fearfulness. Prior to starting the fluoxetine he had a thorough regular vet check (w/full thyroid panel @ MSU) and is in excellent health; and yes, we are working with a behaviorist and are following a behavior modification plan. The fluoxetine is on board solely to help him be more receptive to the training program. First, as to dosing: Our vet initially prescribed the full therapeutic dose of 40 mg/day (so ~1.2 mg/kg for our 75 lb dog), but at our request dropped it to 20 mg/day to start out. We did this because Merlin is prone to GI upset and I was concerned about that and about appetite loss. The plan is to increase to 40 mg/day after 30 days, but I'm just wondering if there's any evidence of therapeutic efficacy at a lower dose in greyhounds? Any idea whether introducing the drug gradually, as we are doing, will help to minimize potential side effects or merely delay them? We began seeing some mild appetite loss within the first week, but nothing too worrisome at this point. He's a bit off his breakfast and suddenly picky about treats, and we are seeing some nausea in the a.m. as well. But he is still eating part of his breakfast and all of his dinner. When might we expect his appetite to improve? Or is it more likely to get worse (e.g., when we increase the dose) before it gets better? Lastly, I believe that appetite loss is the most common side effect of this drug, but are there other things that we should be particularly watchful for? I'm especially concerned about how best to recognize any adverse behavioral effects, e.g., increased depression or anxiety. Thanks in advance - I appreciate any insights or advice based on experiences with your greys. -Michele Quote Merlin (Heathers Wizard), Mina (Where's Rebecca), and Mae the Galga - three crazy dogs in the house of M Link to comment Share on other sites More sharing options...
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