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Osteosarcoma... Genetic?


Guest WhenIGiveIn

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Guest WhenIGiveIn

So Isis my borzoi's half brother was diagnosed with osteo on friday and after a clear chest xray they will amputate the leg. He is a young boy only 5 years old :( So should do well with amputation but its still very sad as you can imagine.

 

I was just wondering if anyone has done any research on genetics in relation to osteo? Cancer ingeneral in genetic but I was just curious HOW genetic osteo is in dogs.

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Well, according to knowlegable people I have talked to, it can be in family lines, but is not certain that it will be passed along. You might see it crop up from time to time, but the fact that Radar has it is probably not a death sentence for Isis, KWIM? That's what makes it so tough to eradicate - there is no way to predict it.

 

But it might not hurt to contact Dr. Couto for his opinion. Maybe he's seen something?

Sarah, the human, Henley, and Armani the Borzoi boys, and Brubeck the Deerhound.
Always in our hearts, Gunnar, Naples the Greyhounds, Cooper and Manero, the Borzoi, and King-kitty, at the Rainbow Bridge.

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Guest WhenIGiveIn

I was thinking of talking to Dr. Couto when I see him at 3Gs. I figure it wont hurt to run it by him. I am in no way flipping out about Isis but the thought definitley crossed my mind.

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I was thinking of talking to Dr. Couto when I see him at 3Gs. I figure it wont hurt to run it by him. I am in no way flipping out about Isis but the thought definitley crossed my mind.

SInce you're talking about a sighthound here, I wouldn't wait, I'd contact Dr. Couto right away about osteo surgery on a sighthound. He has protocols that are important to follow during surgery. In particular, he gives a product/drug that helps greyhounds from bleeding out after surgery. I wonder if this problem is particular to GHs or to all sighthounds--so I'd ask him right away, if possible.

 

DD

Donna
Molly the Border Collie & Poquita the American-born Podenga

Bridge Babies: Daisy (Positive Delta) 8/7/2000 - 4/6/2115, Agnes--angel Sage's baby (Regall Rosario) 11/12/01 - 12/18/13, Lucky the mix (Found, w 10 puppies 8/96-Bridge 7/28/11, app. age 16) & CoCo (Cosmo Comet) 12/28/89-5/4/04

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Guest WhenIGiveIn

I did give Dr. Coutos info to the person that owns Isis's half brother so I think she is going to contact him. Im waiting till then just to ask him about genetic possibilities.

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I think he's investigating the genetic possibilities of OS... can't really remember what he said when I saw him speak but he suspects there is a genetic link.

 

(And that would make sense of the fact that many less Irish & English greys get OS than American greys...)

Jeannine with Merlin, the crazed tabby cat and his sister, Jasmine, the brat-cat

With GTsiggieFromJenn.jpgAngel Cody(Roving Gemini), and Weenie the tortie waiting at the Bridge

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My Marvin passed away from osteo at 7 1/2. I found out in June his littermate Flash had it and he was ent to the bridge. I have Ramm, also a littermate, now 10 and I am worried about him. I contacted Dr. Feeman through this board and asked him about littermates and cancer and mentioned my concerns for Ramm, this is what he replied.

 

I've never seen any published information showing that littermates are at higher risk if another littermate was diagnosed with cancer. That isn't to say that a link couldn't be present, just that one hasn't been established.

 

Sending prayers for Isis' brother.

Nancy with Rocket, Umeko and Sasha

gallery_151_3099_2018.jpg

Missing Albi, Kassie, Ramm, Ruby, my good boy Marvin and Mickey (BT)

 

NANCY B'S COLLARS

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Guest FordRacingRon

Well I dont know about dogs, but I beleive in humans it is genetic and therfore why not dogs. I know for a fact that there are certain markers in DNA that can be checked to see if a person is suseptible to a certain type of cancer. I know this because I am a survivor of kidney cancer and although I was diganosed 4 1/2 years ago, many strides have been made to tell if it is gentically handed down, and even there are DNA tests to tell if certain treaments would work. these tests did not exist even 4 years ago. So if it is possible for humans,,why not dogs?

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According to Dr Couto, research does seem to be pointing towards a genetic link. Doesn't mean all the littermates in one litter will inherit the wrong combination of genes though.

 

I'd definitely check with him if you have the opportunity. Good luck!

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The plural of anecdote is not data

Brambleberry Greyhounds My Etsy Shop

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Guest LynnM

The only generally accepted risk factors are being of a long-boned breed and trauma to the bone- a break, fracture or other insult to the bone at some point in the dog's life. Could there be a link? Sure. If I had two littermates that both had broken bones at some point and one developed osteosarcoma, I'd likely be on pins and needles waiting for the other one to limp. But, nothing's been proven. These sorts of diseases have so many aggravating and mitigating factors... no way to pinpoint just one.

 

Lynn

Edited by LynnM
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Guest longdogs

It's genetic to the point that long-legged, larger bodied dogs are the product of their genes. Nugget's bone specialist, working in a teaching veterinary clinic in the middle of our local greyhound territory, told me he sees a lot more dobermans, rottweilers and other similar dogs than he does greys and they are proportionately more affected. However, osteo must still rank quite high in the list of serious things that ail greyhounds. It does seem to be a product of the additional bone stress in larger dogs.

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Guest LynnM

Around here, it's not even the super long boned breeds- boxers and golden retrievers get it in droves, though to be fair, boxers seem to get EVERY sort of tumor at a higher than normal frequency.

 

Lynn

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If I see DaBones take even an off step, my mind shifts in to what if ? overdrive. Why, you ask? His full brother Zinger had osteo, but that did not take him from us. Bones' half brother Dennis also had osteo and it did take him. I try not to think about it too much. There is not a dang thing I can do about it if it rears it's ugly head in Bones. We will deal with it IF it happens.

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