Non-epitheliotropic Cutaneous Lymphosarcoma

[kikibean]

Hi All-

My friend's 9.5 yr old grey has just been diagnosed with non-epitheliotropic cutaneous lymphosarcoma.

She's having trouble finding anyone w/ any sort of clue about this.

 

Her normal vet wants to send her dog, Ax, to the vet school at the University of Missouri. They're talking radiation & chemo, he'd have to stay for a month and the cost would be about $10,000. No sort of idea on what sort of outcome or life expectancy he would have. She's definately not going this route.

 

The local oncologist is leaning more toward chemo, but again he can't give her any idea of if it would have any success.

 

No one seems to have any idea of the prognosis, other than it's Poor.

 

She's waiting to hear back from OSU.

 

I just thought I'd throw it out to GT to see if anyone has had any experience or thoughts to share.

 

As a side note, one of her other hounds was diagnosed with Lymphoma the same day. They're doing chemo for him. He's not even 7.

[Burpdog]

I would definely contact Ohio State by phone and email.

 

From the Merck manual:

 

Nonepitheliotropic cutaneous lymphosarcoma (NECL) is the most recognized form of cutaneous lymphosarcoma in all domestic animals but dogs and cats. In dogs, NECL is most common in middle-aged or older animals. Lesions are nodules or plaques that most commonly develop on the trunk. They generally are multiple, although solitary lesions may be noted, especially in cats. In many cases, NECL is grossly indistinguishable from the tumor stage of ECL. A definitive diagnosis is important because NECL in dogs is generally more aggressive than ECL, and systemic involvement occurs commonly and early in the course of the disease. Various modes of therapy, including excision, chemotherapy, and less frequently radiotherapy, have been used both singly and in combination. Excision is the choice when the disease is limited to a solitary tumor, and complete cures have occasionally been obtained. Excision or cryosurgery in more diffuse forms infrequently elicit longterm remissions. Chemotherapy or chemoimmunologic protocols used for other forms of canine lymphosarcoma should be considered as palliative. The average remission time is ~8 mo.

 

This mentions the nonepitheliotropic

 

Article

 

Cutaneous non-epitheliotropic lymphoma

Primary cutaneous non-epitheliotropic lymphomas may occur or it may occur as a cutaneous manifestation of the generalized lymphoma. As well as the classical forms, vasotropic and vasoinvasive tumors are also possible. The large majority is of T-cell origin, B-cell lymphomas being very rare. The non-epitheliotropic cutaneous lymphomas are rare, even compared to the epitheliotropic lymphomas. The average age of dogs affected is between 9 - 11 years old.

The classical forms show solitary or multiple nodules or infiltrative plaques in all locations.

 

Article

[Guest VelvetEars]

I'm so sorry to hear this. No experience, just prayers. OSU would be my first contact as well.

[patricia]

I agree with the other posts...contact OSU. Sending my prayers to your friend and her precious babies.

[Guest argolola]

No advice here, but your friend and her pups will be in my prayers.