One of our greyhounds, Finn (8 years old), has been struggling with continuous diarrhea for years - since late 2015 (of course, numerous fecal testing, tick testings, and any other possibilities as much as we could think of, we were told, whatever takes - we have done. Went grey-savvy vets), lost more than 10lbs. finally, we have decided to get consultation with Dr. Couto about his situation (March) and we decided to do endoscopy (colonoscopy) - it was done late April this year. Biopsy came back as "Moderate to severe lymphoplasmacytic entierritis (duodenum, ileum, stomach) with mild secondary lymphangiectasia."
We immediately started with steroid - first we tried Pred and it didn't work Finn well so we switched Budesonide. And we switched hydrolyzed prescription kibbles - no more meat proteins taken. Beside then, he started taking weekly vitamin B12 injection (GI panel revealed his B12 level was extremely low) and tylosin powder with opmeprazole (for ulcer we found through endoscopy). However, we couldn't get the result what we wanted so vet finally prescribed us chlorambucil... started taking it every other day for few weeks; however, again, Finn hasn't respond what we wanted to him so increased dose it to taking every day. It's bee about a week; however, he still hasn't shown improvement.
We are so hopeless right now. We were told if nothing these drugs wouldn't work, that would be the end of option in terms of taking prescription drugs. Regarding hydrolyzed prescription food - we have been trying Purina HA but after trying this for about 4 months, we wonder if that food would not be the best match. We now ordered both Blue Buffalo HA & Royal Canin's HA as we want to try both to see how Finn would respond.
What I'd like to ask you here - if you have any experiences with your greys with IBD; especially, for those who took similar journey as we are taking right now. I am not sure how many people actually deal with steroid + chlorambucil.... Finn started having diarrhea episodes back in October 2015. It has been so long - again we tried as much as we could time to time, back then things we tried were what we believed the best for him but eventually everything was failing. Then we finally decided endoscopy but still we can't figure out why Finn cannot recover despite of all of medications.