CharliesDad

Thanks to all for your replies. Sorry, I didn't post follow-up. Maybe this will help others with worming. (SOrry I don't have time to read the other pertinent threads.) Strider's last fecal was negative for hooks and tapes and he has been flea-free for the past 9 months that I've had him. He was dosed with Panacur for 5 days after he came back from the kennel, but it was not effective for his tapeworm or hookworm. WE redosed with Droncit, and this seemed to get rid of the tapes. For the hooks, we administered Interceptor every 2 weeks for 10 weeks (5 doses). We used Interceptor (no flea-med) because of the shortage of Sentinel. For this reason, my vet wanted him to have a flea-med, so we used REvolution once a month. We made sure that the various meds were administered 5 days or more apart to help avoid interaction probs. To keep the hooks that will always be hiding in his body under control as well as to deal with other parasites, he will be on Sentinel monthly for the rest of his life. From my research, I understand that Sentinel every 2 weeks for 2 months+ is key to killing hatching hookworms during the deworming phase. I received third-party expert opinion by contacting http://www.capcvet.org/ (Companion Animal Parasite Council). It's possible that they have a bias based on funding from pharmaceutical sponsors, but I found the advice balanced and helpful. Sorry it took me so long to post this follow-up. Good luck all with the deworming. CD

Many thanks to all for your contributions to my query! After recheck following 6 weeks 3 x daily dexamethasone, my greyt's neovascularization (new blood vessels) is pretty much gone! Yay! Plan is to continue 2 x daily going forward without EDTA and then recheck in 2 months. He is pretty resistant to wearing Doggles. They impede his vision a lot, I think, so I don't insist very much. I avoid mid-day direct sunlight except for 20-30mins walk. FYI, below is an exchange between my vet and consulting vet ophthalmologist which occurred this week. Thanks again! CD "Hi K, The inflammation present in most cases of pannus include "red" changes - which is a vascular response, which responds well to use of anti-inflammatory drops +/- cyclosporine or tacrolimus. There is also "black" changes which is deposition of pigment secondary to the inflammatory response. The pigmentary changes do improve with ongoing treatment but this can take many months or longer. Then there are "white" changes - a mineral or fatty deposit which typically is located at the leading edge of the inflammatory wave so to speak. This typically does not get better, but by keeping the underlying inflammation at bay we can prevent this from getting worse. EDTA does not penetrate well through intact cornea, so typically I will use it in situations where mineralized deposit is being sloughed off as we see in very old dogs with corneal degeneration. Hope this is helpful, M Z On Wed, Sep 11, 2013 at 9:55 AM, Dr. K H wrote: Hi Dr Z.., I have a question about atypical pannus in a greyhound ...the eye lesions are as follows: bilaterally symmetrical - extending from lateral sclera to lateral corneal surface, there is mild neovascularization that ends in a white squiggly line-like corneal opacity I have been treating it with Maxidex (dexamethasone) ophthalmic TID (3xdaily) for the past 6 or so weeks and all the neovascularization has resolved, however the white squiggly line is still present – corneal deposit? Scar? It had been suggested to use EDTA ophthalmic, but it is on back order. Will cyclosporine help scarring, or will it only prevent it from getting worse? If this is in fact a corneal deposit, would this help? Thank you so much, Sincerely, Dr K H"

Hello Forum, I searched our forum threads on pannus but did not find information about treating the condition with EDTA (Ethylene Diamene Tetraacetic Acid). Strider (my 4 year old male) was diagnosed with pannus about 7 weeks ago. Since then I have been applying 0.1% dexamethesone ointment (Maxidex) to his eyes 3 x daily. At his follow-up 3+ weeks ago, our vet observed that the neo-vascularization (extra blood vessels) had diminished but that the opaque squiggly line (scarring and pigmentation at the edge of the film growing out from the the upper temporal (outer) region of the eye) was unchanged. At his next follow-up, I am anticipating that our vet will propose treating the scarring with EDTA, (said to have lipid-calcium binding effects) on the advice of our local ophthalmologist. Does anyone on Greytalk have experience with EDTA in pannus treatment? Also, I have read about treatment of pannus by cyclosprorine (an immunosuppressant?) in conjunction with a steroid like dexamethesone, and not just dexamethasone alone. Do you have any feedback? Thanks!

Milbemycin and selamectin are ok to use together, but I'm wondering why your vet is recommending Revolution for fleas? I'm also not sure I understand what the significance is of him living in a kennel for 9 months? Did he have fleas and does he still have them? Do you have a flea infestation in your house? Thanks for your help, Dr. Jennifer! I will pass on your view re milbemycin and selamectin. It is similar to the feedback another vet emailed to me. Re fleas: from what I understand from my vet, she is concerned that Strider may still have fleas at some life-cycle stage in his body. She feels it's likely he has fleas because he lived from March - November in a greyhound adoption kennel with a lot of new greyhound arrivals every week/few weeks. He was given a Capstar on Nov 17 and a dose of Revolution was applied to his skin on Nov 19 (I know you've stated your preference for Trifexis over topical, but my vet wasn't familiar with Trifexis and I wanted to go with a better-known product). Our current plan is to separate the Revolution from the Interceptor dose by 5-7 days. Would you say that his kennel stay has not make it likely that he has fleas or ever had fleas? Do you have any other input re flea treatment? Or maybe that's for another thread. I will also mention to my vet your other helpful input above as we consider our next steps: The main idea I get from this thread and elsewhere is to repeat dose over a few weeks. Different vets differ on the precise timing and the most effective medication. The view I am developing is to combine an dewormer like Strongid or Panacur with milbemycin (Interceptor) over about 6 weeks. While she has her own views, my vet is open to my researched opnions, which I appreciate. Thanks again, Dr. J! Enjoy your wonderful four-legged friends! They look beautiful!

Thanks for your help, Cindy. Sorry about the pics! I have had some trouble uploading. I will try again!

Hi all, Strider (KB's Skipper/ former call name Fudge) is settling in really well. I mean, REALLY WELL! Home alone for 3.5 hours. Teeth brushing. Wears winter boots. Eating well. BM's good. Socializes well with with humans and canines. I'm sooo blessed! A former dog owner gave my vet their unused Inteceptor, and my vet passed it onto me at no cost, for which I am VERY grateful. Here's the hookworm treatment protocol we're considering: 2 x 10 ml doses of Panacur for five days Nov 19 - 24 (now completed) Interceptor every two weeks starting Dec 8 (i.e. 2 weeks after Nov 24) then Dec 22, Jan 5, Jan 19 and Feb 1. Retest fecal 2 weeks later. This protocol is suggested as a way to manage "larval leak" phenomenon which may occur with hookworm infestations. http://www.vetauctio...i/gi-p1-19.html "Larval leak" occurs when some larvae in hypobiosis are activated and make their way into the intestine. Activated larvae can then follow one of two pathways: Larvae can migrate directly to the intestine where they will reach maturity. Larvae can enter the circulatory system and travel to the lungs, where they escape into the alveolar space. Larvae then migrate up to the trachea, are coughed up and swallowed by the pet, and travel to the intestines where they reach maturity (tracheal migration)." One concern is that he was started on Revolution for heartworm and fleas on Nov 19 (at that time we had no Interceptor or Sentinel available). Vet says he needs at least 2 more doses of Revolution to deal with possible fleas, since he was living in a kennel for 9 mos. Can he tolerate a dose of Revolution approximately 30 and 60 days after Nov 19 along with the the Interceptor every two weeks? Is medicating at the same or similar times with milbemycin (Interceptor) and selamectin (Revolution) contraindicated? Thanks for any feedback. CD

Hello Board, I've been studying our board re hookworm. Apart from several useful posts in this thread, I found these posts in other threads helpful: and Here's my plan: Confirm that my vet plans a second round of treatment with Panacur or Drontal-Plus even if the stool sample comes back negative. In light of absence of Interceptor, ask my vet when it will be safe for Strider to go on Trifexis (He was dosed with Revolution on Nov 19) Dose with Trifexis and see how he reacts. He doesn't seem to have a sensititve digestive system, so I think there's a good chance he won't throw it up. Wash bedding with bleach and pour bleach mixture on areas where I picked up his poop. (We didn't get freezing temps here last night). Wipe his butt after he does a BM -- and make sure I dispose of wipe and wash my hands carefully! I welcome your feedback and I'll keep you posted about results. BTW, he's settling into his new home very well. He's a beautful boy! Has even let me brush his teeth after only 4 days with me!!! CD

Thank you, dante2zoe and JJNg for your helpful feedback! I got adopted by Strider (my new name for him) (KB's Skipper/ former call name Fudge) at Northern Greyhound Adoptions in St. Alban's, Vermont this past Saturday! Yay! His medical confirmed that he's healthy except for hookworm eggs in his stool sample. He got a dose of Revolution yesterday and we started him on oral suspension Panacur, 10ml 2x daily for 5 days. We will test his stool again in a month. I may use Trifexis in the future. Thanks again for your suggestions and all the best to everyone with your greyt greys! CD

Hi all! I'm planning to be adopted by a new grey on Nov 17 (Saturday)!! Yay! Our adoption coordinator plans to give him/her Capstar at the kennel prior to our drive home (about 4 hours), and then I planned to bathe the dog with Adams Flea and Tick upon arrival back at the house. I have a vet appt on Monday and am debating what worm and flea prevention med to give but am leaning towards Trifexis even though there seem to be SOME bad reports out there on the web about Trifexis. Does the forum have any further experience with this medication to report? Does Saturday- Capstar + Flea Shampoo then Monday - Trifexis + another vaccine that the vet may recommend = too much medication? Thanks in advance for your feedback! CD PS My vet proposed as an alternative to Trifexis: "Another option would be Revolution, although it doesn't kill hookworms or whipworms very well. We could combine it with Panacur (fenbendazole) once monthly, if you'd like. BTW, Revolution kills all stages of the flea life cycle."

Thank you to Adrienne and others for posting on this topic. Charlie currently has 5 corns on 4 paws. My sister, who is an esthetician, says that when she files callouses for people, it typically causes the callous to grow back even more. The skin gets the message to grow more of the protective type of skin. My experience with Charlie is similar -- his corns and callouses grow back with a vengeance after hulling and filing down with a dremel. Due to the Canada Post labour dispute, I am waiting to order the Hyaluronic acid and the corn cream. I am currently applying organic olive oil and then wrapping his feet with warm damp cloths inside baggies for the 20 minutes, waiting 5 minutes and then applying Thuja essential oil, which is supposed to treat certain types of warts. It seems like persistence and daily treatments is the name of the game with these miserable little corns!!!

Here is a more up-to-date thread on this topic http://forum.greytalk.com/index.php/topic/270587-weve-started-the-murray-ave-corn-cream/

Hi all, Charlie currently has 5 corns on 4 paws. My sister, who is an esthetician, says that when she files callouses for people, it typically causes the callous to grow back even more. The skin gets the message to grow more of the protective type of skin. My experience with Charlie is similar -- his corns and callouses grow back with a vengeance after hulling and filing down with a dremel. I am treating the corns with Thuja oil at the moment, but I'm going to try the Murray Ave products if they can ship to Canada. How is the treatment working for other greyts/dogs? ANy more feedback?

Sorry, can't edit my post any more. Just to add, I don't like what I read about the body system impact and $ cost of CYCLOSPORINE (ATOPICA).

Hi all, CHarlie is having a very itchy time. It's his fourth year for these symptoms, which he gets August - September. Last year he was on Vanectyl-P again (Trimeprazine tartrate 5 mg, and prednisolone 2 mg, per tablet -- I think the brand name is different in the U.S.) for an extended period. He lost a lot of fur in November, indicating to me that the drug interacted badly with his system. I want to avoid this med if I can. This website says not to use steroids if they become necessary, so I will consider that opinion. : http://www.marvistavet.com/html/body_itch_relief.html I may consider a topical steroid, but how do I apply it without him licking it? Boots seem to make things worse due to reduced circulation and unevaporated sweat. I have him coned almost full-time. His front paws are swollen from licking and nibbling. His swelling has subsided a bit since the dreaded cone has been introduced. The paws are the most affected area. The area between his toes has a strong odour. Bathing his feet in baking soda doesn't seem to have been effective and may dry out his skin. Maybe I should just rinse his paws in water when we come in from the walk. I will try the corn starch suggested by Newgreymom. I may have used too strong a baking soda solution. Charlie is 75lbs/34kgs. I am using fish oil supplements along with 3 x 25 mg Life brand diphenhydramine hydrochloride. This is generic Benadryl. (There are other generic Benadryl mixtures that contain substances that are harmful to pets.) My vet says I can use 75mgs up to 3 x/day. This seems high but concurs with Milosdriver above. The anti-hystamine does seem somewhat to help at this dosage, which I started 2 days ago. Maybe I need to consider another anti-hystamine. Tavist does not seem to be available in Canada. Atarax is available in generic form in Canada by prescription. Chlorpheniramine seems to be sold as Chlor-Triptolon in Canada. I will ask my vet about this. I am going to look for a colloidal oatmeal bath that does not contain soap/soap-like ingredients, which can take away his natural skin oils and defeat the purpose.. I want him to soak in it, or at least his paws. TEN minutes of skin contact seems to be recommended, but it's hard to get Charlie to stay in the bath that long. Aveeno seems to have something available in small pouches. That's my report. I welcome feedback. I wish all of you and yours greyt itch-free days!

SOrry, I forgot to report back. My vet did do an analysis of first pee and those urine results confirmed that all is well re kidneys. I'm glad my vet's thorough, although it's a few more $$ to be sure. I will post on another thread now about Charlie's skin condition and allergies. Thanks all!