Another fan of Transfer Factor here! I first used it for my weimaraner who had hemangiosarcoma. I feel it really contributed to extending her life. The specialist gave her 6 weeks to live at the time of her diagnosis. I lost her to congestive heart failure 13 months later. Twelve and a half of those months were excellent quality.
I've also recently given it to my greyhound, Carly, who is allergic to flea bites. One bite can set off a vicious cycle of itching, scratching, and chewing and within no time she'll be bleeding. This year she's MUCH better and I think it's the Transfer Factor.
Hope you find relief for them soon. Allergies are very frustrating.